Both sides go for 4-3-3 systems which creates an intriguing match up of who can get the better of the game.
Fiorentina: (4-3-3) Sportiello; Laurini, Pezzella, Astori, Biraghi; Veretout, Badelj; Chiesa, Benassi, Théréau; Simeone.
Stefano Pioli names an unchanged team from the side who beat Sassuolo 3-0. Simeone will lead the line and be looking to add to his five goals this season. Fiorentina have Cyril Thereau alongside him looking to keep his impressive season going.
Napoli: (4-3-3) Reina; Hysaj, Albiol, Koulibaly, Mario Rui; Allan, Jorginho, Hamsik; Callejon, Mertens, Zielinski
Napoli are without key player Lorenzo Insigne who was injured against Feyenoord. Zelinski will be part of the front three including the dangerous Jose Callejon and Dries Mertens.
How to watch?
If you're in the UK you’re in luck. This one is on BT sport although its on at 2:15, so check out our twitter for full updates or join the conversation in the comments below before the coverage starts. For safe legal streams check here.
Any links to illegal streams posted in the comments will be deleted, and the person responsible will be banned from the site.