Laurini's injury gives Gaspar a chance at right back, heres to hoping he doesn't have another 'moment' like he did against Juventus. Pezzella and Astori make up a predictable back two, hopefully the latter has developed some brain cells since his last outing. Dias gets back into the squad which is fantastic news, and he is joined by Chiesa and Simeone.
For Roma, Gerson gets a rare start alongside El Sharaawy and Dzeko. Pellegrini and Gonalons fill in for De Rossi and Strootman in what is sure to be a move with fitness in mind. Manolas replaces Jesus after his midweek game against Chelsea, with Fazio, Florenzi and Kolarov completing what is a pretty formidable back line.
Fiorentina (4-3-3): Sportiello; Biraghi, Astori, Pezzella, Gaspar; Veretout, Badelj, Benassi; Chiesa, Simeone, Dias.
Roma (4-3-3): Alisson; Florenzi, Manolas, Fazio, Kolarov; Gonalons, Pellegrini, Nainggolan; El Sharaawy, Dzeko, Gerson.
How to watch
The game is being shown live on BT Sport 3 (UK), but if you're outside the UK, you can find a list of safe, reliable streams here.